Pharmacokinetics: Drug Dosing in Renal Disease

Learn how renal disease affects kidney function and how to apply dosing regimens

On this course, you will learn the principles of pharmacokinetics and drug dose adjustment in patients with renal disease. You will be introduced to basic kidney physiology and functions, including the filtration, secretion and reabsorption of water, and the mechanisms of renal drug excretion.

You will learn how to calculate renal clearance, and how to recommend dosing regimen for patients with the disease. You will also explore the general principles for dosage adjustment in dialysis patients, and be able to describe the typical clinical presentation of chronic renal failure.

This course is for anyone requiring clinical pharmacokinetic knowledge, including undergraduate pharmacy students, post-graduate pharmacy students and pharmacists in clinical practice.

This course is for anyone requiring clinical pharmacokinetic knowledge, including undergraduate pharmacy students, post-graduate pharmacy students and pharmacists in clinical practice.

• Explain basic physiology of the kidneys
• Calculate renal clearance by excretion rate method / renal clearance by urinary recovery method
• Describe pharmacokinetic factors that affect dialysability of drugs
• Describe the most common causes of chronic renal failure
• Assess an appropriate therapy for chronic renal failure and secondary complications