Principle Scientist II / Senior Principle Scientist (PK Science)

Job ID REQ-

Mar 26, 2025

United Kingdom

Summary

50 + projects are being supported in the Immunology Therapeutic Area within the PK Sciences department. We provide PK and PK/PD strategies from early discovery all the way through to registration and beyond. The Immunology portfolio represents a balanced and broad portfolio of modalities spanning from classical small molecule candidates over to targeted protein degraders, and multiple variants of biologics modalities extending to CAR-T cell therapies and T-cell engagers. Since our portfolio is growing, our Team likes to expand by adding a Team member who will drive projects through Project Start and Lead Optimizations incl. First-in-Human (FiH) and all clinical phases.

Your Responsibilities

1. Independently represents PK Sciences as a core member of cross-functional Teams supporting projects.
2. Leads a PKS sub-team to define and implement PKS strategy for compound progression and development.
3. Analyze and interpret PK/PD/IG data generated during and present results to the program.
4. Proactively identifies potential project hurdles, provides solutions, and contributes to contingency plans.
5. Presents PKS plans at various review boards and seeks approval for overall project strategy and budget.
6. Publishes internally or externally as main contributor to enhance Novartis and PK Sciences visibility.

Please note this is a hybrid role - there is a requirement of a minimum of three days on site in the London office per week or twelve days a month. We are unable to offer permit sponsorship for this role.

About the Role

What you'll bring to the role:
• Ability to work in and adapt to a changing scientific & regulatory environment.
• A strong team player, demonstrating excellent communication skills with experience in leading cross-functional teams.
• A curious mind and a genuine interest in collaborative interactions across disciplines.
• PhD, MD or PharmD in life sciences/healthcare.
• Credible background and in-depth expertise in drug candidate profiling for progression to FiH.

Why Novartis? Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us!

Commitment to Diversity and Inclusion

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility & Accommodation

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