Scientist

Scientist - Characterization expert in colloidal and nanoparticulate systems

Purpose:

The scientist will join the Advanced Materials Characterization and Investigations (AMCI) group within Analytical Development. AMCI is an international and diverse team of scientists performing advanced analytical characterization of pharmaceutical products and leading global analytical investigations for the commercial product portfolio and for the Discovery, Product Development & Supply (DPDS) organization.

Join our team as a Senior Scientist specializing in Particle Technology. In this lab-based role, you will have the exciting opportunity to characterize particulate systems, focusing on colloidal suspensions, peptides, gels and liposomal drug product formulations

You will be responsible for:

Study nanoparticulate and colloidal systems such as nanocrystalline suspensions, oligonucleotides, (hydro)gels, micellar and self-emulsifying drug delivery systems (SMEDDS), liposomes, etc. with state of the art analytical technologies and collaborate with CMC and drug product development teams to design the best product and process to meet the therapeutic product profile

Develop as subject matter expert, design, lead and perform experiments in the analytical development for colloidal systems

Apply state-of-the art science to ensure a targeted approach to problem solving and delivering relevant results

Work in a multidisciplinary team of researchers and show willingness to learn/explore new techniques

Act quickly, lead and provide expertise and solutions for investigations on commercial products

Develop test procedures and write scientific and investigations reports

Ensure compliance with regulatory requirements, GMP and safety

Stay up to date with the scientific literature

Initiate and follow up collaboration with external partners and universities

Provide input to investment plans to consolidate (and expand) capabilities

Qualifications / Requirements:

Education & Experience

• PhD in Chemical (Bio)Engineering, Pharmaceutical Sciences, Chemistry, Physics, or equivalent by experience in a relevant area.
• Expert in state of the art analytical techniques to study nanoparticulate and colloidal systems such as, scattering techniques (DLS, SAXS, (SEC)-MALS), zeta potential, (electron) microscopy, sedimentation and turbidity related technologies, rheology, flow imaging etc.
• Knowledge on colloidal stability and factors that influence stability
• Good background on preparing dispersions, tailoring dispersion stability and the relation of particulate and dispersion properties to suspension rheology
• Ensure high scientific quality standards for experiments and take responsibility for the results
• You have good project management skills as well as communication skills (oral and written) allowing effective interactions with all levels of the organization.
• You are a team player, able to work in matrix teams and Fluent English (both spoken and written).

Competencies

• Fast learner with scientific curiosity, self-steering, pro-active, creative.
• Open-minded, with ability to work together as one team in a global environment.
• Good written and spoken communication and presentation skills in English.
• Efficient, flexible, dynamic, results and performance driven.