Screening Associate Scientist

Site Name: UK - Hertfordshire - Stevenage
Posted Date: Feb

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Screening Associate Scientist

We are seeking a highly motivated and detail-oriented lab-based Associate Scientist to join our Screening Department. The successful candidate will work within a multidisciplinary team to support the discovery and development of new drugs through high-throughput screening and other screening methodologies. This role sits in the Discovery Biology and Screening (DBS) department, part of a larger Research Technologies platform organisation forming the foundation for GSKs medicine discovery.

This role is based at our GSK site in Stevenage and is an on-site, lab-based position.

Key Responsibilities:

• Perform screening assays to identify potential drug candidates.
• Design, execute, and interpret mechanistic experiments to support drug discovery projects.
• Develop, optimize, and validate screening assays using various techniques such as biochemical assays and cell-based assays.
• Analyse and interpret screening data, ensuring accuracy and reproducibility. As well as maintaining accurate and detailed laboratory records and documentation.
• Collaborate with cross-functional teams including medicinal chemistry, program teams, and data scientists to advance screening projects.
• Operate and maintain laboratory equipment, including automated liquid handlers, plate readers, and other relevant instrumentation.
• Present research findings to internal teams and stakeholders.
• Adhere to all safety and compliance regulations and ensure a safe working environment.

Why You?

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• BSc in Biology, Biochemistry, Pharmacology, or a related scientific discipline, or equivalent industrial drug discovery experience.
• Proven relevant laboratory experience, preferably in a pharmaceutical or biotechnology setting.
• Experience with screening and assay development with proven attention to detail and commitment to quality.
• Proficiency in laboratory techniques such as cell culture, enzyme assays, and other plate-based screening methods.
• Experience with data analysis and curve fitting software (e.g. Spotfire, GraphPad Prism).
• Excellent organizational and time management abilities as well as effective communication and teamwork skills.

Preferred Qualifications & Skills:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• Experience in designing mechanism of action studies and/or target validation.
• Strong knowledge of and/or experience in multiple molecular and cellular biology techniques, including Imaging, Mass Spectrometry, and flow cytometry.
• Strong knowledge and/or experience with different molecular modalities, such as small molecules, ADCs, PROTACs and oligonucleotides.
• An understanding of Digital Fluency and how it applies to drug discovery.

Closing Date for Applications: Friday 28th February 2025

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements. The information that you have provided in your cover letter and CV will be used to assess your application.

GSK R&D

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We're uniting science, technology and talent to get ahead of disease together.

Find out more:

Our approach to R&D .

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class ( US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.