Compute System Manager & Cryo-EM Application Specialist

Work Schedule

Environmental Conditions

Job Description

Compute System Manager & Cryo-EM Application Specialist

When you are part of Thermo Fisher Scientific, you'll do exciting projects, and join a team that values performance, quality and innovation. As part of a successful, growing global organization you will be encouraged to perform at your best. With revenues of more than $40 billion and the largest investment in R&D in the industry, we give our people the resources and chances to create significant contributions to the world.

Location/Division Specific Information

Join our dynamic Life Sciences Business Unit team and the TEM Center-of-Excellence in Eindhoven, the Netherlands. We are dedicated to revolutionizing cryo-electron microscopy, a groundbreaking technology that has accelerated the development of cures and vaccines and deepened our understanding of disease pathways.

Discover Impactful Work:

Cryo-electron microscopy has revolutionized structural biology. Its adoption in academic and pharmaceutical research has increased our understanding of disease pathways and has accelerated development of cures and vaccines. Thermo Fisher continues to innovate technology at a high pace to rapidly enable more scientists to access these techniques.

We are seeking an experienced Cryo-EM Application Scientist with a background in computing to join our team. The specific responsibility will be to set up, maintain and manage our compute infrastructure for Cryo-EM and Cryo-ET data processing.

A day in the Life:

Manage and maintain the compute setup, ensuring optimal performance and security. This includes system setup, configuration, troubleshooting, software and hardware updates, and backups. Work closely with the IT team and site infrastructure team to plan and scale the high-performance compute capabilities to meet the needs of the team.

Perform hands-on Electron Microscopy (EM) work for data collection on customer and in-house samples to support sales, marketing as well as internal R & D projects. Process and analyze electron microscopy datasets using both established and emerging software packages. Stay up to date with the latest advancements in processing methods, software, and associated IT infrastructure.

Collaborate with internal and external researchers and scientists to understand their requirements and provide technical assistance with data processing. Contribute to the development of new microscopy technologies and the implementation of new methodologies for data processing and analysis.

Keys to Success:

This position is ideal for an experienced electron microscopist with a deep familiarity of cryo-EM and cryo-ET data processing, with emphasis on compute hardware, software, user management and networking. The ideal candidate will possess the following combination of education, experience, and skills:

PhD degree or equivalent with solid understanding of data processing for Life Sciences EM, Structural Biology, or X-ray crystallography.

Experience interacting with highly technical customers and the ability to communicate sophisticated technical concepts to a variety of audiences. Access to a strong customer network within academia and pharma industry.

Ability to independently identify , define and implement solutions in a highly dynamic technical environment, specifically:

• Experience deploying compute nodes and storage servers/SANs in a datacenter or hybrid environment. Cloud experience is a bonus.

• Experience in architecting, setting up, maintaining , stress-testing, and benchmarking professional CPU/CPU+GPU CUDA compute nodes in a heterogeneous OS environment (Linux + Windows). Experience in setting up and maintaining compute environments to enable cross/multimode compute is a bonus.

• Experience with high-capacity, high performance storage ( TrueNAS , WEKA, VAST, etc ) requirements, configuration, and provisioning. Proficient in planning, installation, configuration, and upgrades of a SAN architecture. Plan, architect, and deploy storage projects and solutions for backup, data protection, performance, and upgrades.

• Experience with SMB, CIFS, NFS, ZFS storage presented to a wide array of systems including both Linux clients as well as Windows file services and desktop clients.

• Periodic reports on storage capacity and utilization and system uptime and performance. Support for critical issues and complex projects. Supervising of all storage for integrity, reliability, resource utilization and availability.

• Willing and able to travel internationally up to 20%.

Benefits

We offer competitive remuneration , annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!