PhD Researcher (f/m/x) Studying the metabolic interaction within a microbiome model system, focusing on the production of nucleotides

logo Scientist (m/f/x) - UFZ - logo The UFZ has a strong commitment to diversity and actively supports equal opportunities for all employees regardless of their origin, religion, ideology, disability, age or sexual identity. We look forward to applications from people who are open-minded and enjoy working in diverse teams. Place of work: Leipzig Working time: 65 % (25,35 h/week) Contract limitations: limited contract / 3 years Salary: Remuneration according to the TVöD public sector up to pay grade 13 including attractive public sector social security benefits. Application deadline: 10.11.2024 Your contact for any questions you may have about the job: Prof. Martin von Bergen Please submit your application via our online portal with your cover letter, CV (please omit your photo, age, or marital status) and relevant attachments. Apply now More information about jobs at the UFZ: Helmholtz-Zentrum für Umweltforschung GmbH - UFZ Permoserstraße Leipzig, Germany The Helmholtz Centre for Environmental Research (UFZ) with its 1,100 employees has gained an excellent reputation as an international competence centre for environmental sciences. We are part of the largest scientific organisation in Germany, the Helmholtz Association. Our mission: Our research seeks to find a balance between social development and the long-term protection of our natural resources. PhD Researcher (f/m/x) Studying the metabolic interaction within a microbiome model system, focusing on the production of nucleotides The job We are seeking an enthusiastic PhD Researcher (f/m/x) to study the metabolic interaction within a microbiome model system, focusing on the production of nucleotides in the Department of Molecular Toxicology. The DFG-funded project aims to decipher nucleotides' role in the human microbiome model system SIHUMIx. Your tasks Cultivate the SIHUMIx consortium in anaerobic continuous bioreactors and manipulate specific species by the CRISP/CAS approach Characterize the effects of modified gene expression of selected species on the metabolomic level of the various species and the overall community metabolism by mass-spectrometry-based targeted and untargeted metabolomics and metaproteomics Integrate the omics-results with bioinformatic approaches and also with the results from genome-based metabolic modelling to identify pathways of metabolic regulation within the various species and in the species-species interaction Participate in laboratory group meetings including presentation of results Present your results at international conferences and prepare publications in peer-reviewed scientific journals We offer Excellent supervision and optimal professional and interdisciplinary qualification through our HIGRADE graduate programme The freedom to master even the most demanding challenges between basic research and practical application The opportunity to work in interdisciplinary, international teams and benefit from a wide range of perspectives First class integration into national and international research networks to work together on global challenges Excellent research infrastructure and research data management to optimally support your work A wide range of options for balancing care responsibilities and work through our family office Competent support and advice for international colleagues arriving at the UFZ from the 'International Office' Special annual payment, capital-forming benefits and subsidised Deutschland-Job-Ticket A workplace in a vibrant region with a high life quality and social and cultural diversity Your profile M.Sc. degree (or near completion) in biochemistry, microbiology, bioinformatics or related fields Experience in cultivation of bacteria Profound knowledge of microbiology Strong interest in mass-spectrometry-based analysis of metabolites and proteins Strong interest in bioinformatics Excellent English skills Ability to organize and prioritize work efficiently Charter der Vielfalt LogoTotale logo