Principal Statistician within Clinical Trials

Site Name: UK - London - New Oxford Street

Posted Date: Dec

Please note this position will follow GSK's standard Performance with Choice hybrid work model, which includes 2-3 days onsite at either our London or Stevenage office.

Clinical Statisticians are highly prized and urgently needed at GSK to grow an industry-leading team to ensure high quality quantitative reasoning is at the heart of every project in the portfolio. Our role is essential to ensure we maximise the use of every single data point available to efficiently determine translational strategies that are the foundation of our end-to-end clinical development plans. We need exceptionally talented and committed Statisticians like you to apply your statistical skills and innovative statistical methodology to drive key contributions to the development of new medicines.

The Early Development Statistics (EDS) group is seeking an exceptional Principal Statistician to strategically plan and execute the full lifecycle of clinical trials, from design through to the reporting of Phase 1 and PoC studies. This role involves working within a cross-functional team to draft clinical trial protocols, serve as the statistical representative during its presentation at the Protocol Review Board, and develop Statistical Analysis and Randomisation plans. It also encompasses ongoing study management, reporting, and close-out activities. The EDS group supports all therapeutic areas within the Respiratory and Immunology Research Unit, including infectious diseases. The team is dedicated to employing innovative clinical trial designs and statistical methodologies, with a particular focus on Bayesian techniques, to enhance the probability of program success.

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

In this role you will:

• Provide statistical input for the design, analysis, reporting, and interpretation of clinical studies.
• Build and maintain strategic working relationships with internal and external partners to achieve study deliverables.
• Collaborate within a cross-functional team to ensure study objectives are met.
• Identify and apply innovative statistical methodologies to support the development of medicines.

Why you?

Basic Qualifications & Skills:

We are seeking professionals with the following essential skills to help us achieve our goals:

• Education: MS (or equivalent) in statistics.
• Experience: Relevant experience as a study statistician in a clinical trial setting.
• Statistical Expertise:
  • Practical understanding of statistical modelling and its application to real-world clinical problems.
  • Sample size calculations across various endpoint types.
  • Modelling and analysis of longitudinal data.
• Interpersonal Skills:
  • Excellent communication abilities, with a proven capacity to explain both novel and standard statistical approaches to scientific and clinical colleagues.
  • Strong experience in building and maintaining effective working relationships in a team environment.
  • Ability to adapt to dynamic work settings.
• Programming: Proficiency in relevant programming languages such as R or SAS.
• Performance: Proven track record of strong performance in either an academic or industry setting.

If you possess these skills and experiences, we invite you to apply.

Preferred Qualifications & Skills:

Please note the following skills are preferred but not required. If you do not possess them, we still encourage you to apply:

• PhD in statistics.
• Experience with Bayesian methods.
• Expertise in multiple statistical methodologies and their practical application.
• Ability to apply innovative statistical thinking.
• Strong influencing skills effectively utilised across functions and organisation levels.
• Experience in working with and coordinating the work of CROs.
• Proficiency in time management and prioritisation.

Closing Date for Applications - 10th Jan 2025 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class ( US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.