Senior Research Leader (Biologics Design), London

Isomorphic Labs is an Alphabet company that is reimagining drug discovery through a computational- and AI-first approach.

We are on a mission to accelerate the speed, increase the efficacy and lower the cost of drug discovery. You'll be working at the cutting edge of the new era of 'digital biology' to deliver a transformative social impact for the benefit of millions of people.

Come and be part of a multi-disciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring, collaborative and entrepreneurial culture.

Isomorphic labs are seeking a Senior Research Leader or Research Leader in biologics based drug discovery to capitalise on the potential of our platform in the design of macromolecule based therapeutics. This represents a significant opportunity for a hands-on leader to shape the future of generative de novo antibody and protein based therapeutics design.

Your experience in biologics, coupled with strong existing industry networks, will be essential in establishing and maintaining relationships with key partners in implementing the platform to generate novel biological therapies.

• Build, grow and lead a multidisciplinary team to deliver an industry leading AI/ML based biologics design platform
• Work with Isomorphic labs' business development and executive leadership teams to establish and implement partnerships and integrative strategies to deliver biologics based therapeutics
• Provide end to end leadership of Isomorphic labs biologics strategies working effectively with key internal and external partners to ensure biologic drug discovery program milestones and objectives are met within agreed timelines and budgets
• Manage and deliver on biologics internal portfolio and collaboration projects

• PhD or equivalent experience focused on oncology or immunology or other relevant life sciences research
• Track record of leading end to end biologics discovery programs
• Significant experience leveraging ML techniques for biologics design
• Knowledge of key stage gate exit criteria for a portfolio program
• Experience managing program timelines and reporting data at governance/leadership meetings
• Experience managing multi disciplinary teams
• Experience managing external collaborations including academic/CRO interactions to develop therapeutic antibodies

• Hands on experience of building de novo biologics design platforms
• Project experience across multiple biologics platforms
• Experience of developing drug targeting e.g. ADCs and functional therapeutic antibodies
• Experience managing budgets